Trajectories of Antidiabetic Medication Adherence in Older Adults and the Effect of Depression and Anxiety Symptoms
Authors' conclusion
Older patients with diabetes mostly depicted high adherence. Depression or anxiety did not impact adherence trajectories. However, our study was underpowered to detect small-to-moderate effects of these common mental health disorders.
Study context
- Population
- Older adults who were prevalent users of antidiabetic medications
- Participants
- 282 adults
- Comparison
- Presence vs absence of common mental health disorders
- Primary endpoint
- Adherence trajectories to antidiabetic medications, measured using claims data
- Follow-up
- 12 months
Methodological detailsgroup-based trajectory modeling, multinomial logistic regression, claims data
- Group-based trajectory modeling
- Multinomial logistic regression
- Claims data
Primary result
As reported in the abstract
Adherence trajectories
Low adherence
6.7%
Fair adherence
18.1%
High adherence
37.9%
Nearly perfect adherence
37.2%
Further findings
Association of common mental health disorders with adherence trajectories
- No significant association, even after adjusting for potential confounders
Original publication
Trajectories of Antidiabetic Medication Adherence in Older Adults and the Effect of Depression and Anxiety Symptoms. Endocr Pract. Published 21 June 2025. doi:10.
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