Trabecular Bone Score (TBS) Varies with Correction for Tissue Thickness Versus Body Mass Index: Implications When Using Pediatric Reference Norms
Main finding · TBS valueResult — go to the resultMean difference 0.06Authors' conclusion
These systematic differences preclude the development of a simple formula to allow conversion of TBSBMI to TBSTH "equivalents."
Study context
- Population
- Healthy youth
- Participants
- 189 participants
- Exposure
- TBS by tissue-thickness algorithm vs body mass index (BMI)-adjusted algorithm
- Outcome
- TBS value
Main finding
As reported in the abstract
Mean difference
0.06
P < 0.0001
Observational data: associations, not effects.
Further findings
TBS Z-score using TBSBMI against Bone Mineral Density in Childhood Study (BMDCS) TBSTH reference values
- Falsely higher TBS Z-score; mean difference (IQR 0.3 to 1.6)
- 0.73
Original publication
Trabecular Bone Score (TBS) Varies with Correction for Tissue Thickness Versus Body Mass Index: Implications When Using Pediatric Reference Norms. J Bone Miner Res. Published 13 February 2023. doi:10.
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