Time Trends in the Incidence of Diabetic Ketoacidosis Leading to Hospital Admission Among Adults With Type 1 Diabetes: A Nationwide Danish Register Study
Authors' conclusion
The incidence rates of DKA are declining for all ages, with an overall decline from 2008 for both men and women. This likely reflects improved diabetes management for individuals with type 1 diabetes in Denmark.
Study context
- Population
- Adults aged ≥18 years with T1D identified from a nationwide Danish diabetes register; Diabetic ketoacidosis (DKA) admissions from the National Patient Register
- Participants
- 24,718 adults
- Outcome
- Incidence of hospital admission due to DKA by age, and its time trend
- Follow-up
- 1996 to 2020
Methodological detailsFollow-up 1996 to 2020
- Follow-up 1996 to 2020
Main finding
As reported in the abstract
DKA incidence rate by age
DKA incidence rate, age 20 to age 80
3.27 to 0.38 per 100 PY
Observational data: associations, not effects.
Further findings
Time trend of DKA incidence rate · 1996 to 2008
- 20-year-old individual
- 1.91 to 3.77 per 100 person-years (PY)
- 80-year-old individual
- 0.22 to 0.44 per 100 PY
- Incidence rate of DKA increased for all age-groups
Time trend of DKA incidence rate · 2008 to 2020
- 20-year-old individual
- 3.77 to 3.27 per 100 PY
- 80-year-old individual
- 0.44 to 0.38 per 100 PY
- Subsequent minor decrease in incidence rate
Original publication
Time Trends in the Incidence of Diabetic Ketoacidosis Leading to Hospital Admission Among Adults With Type 1 Diabetes: A Nationwide Danish Register Study. Diabetes Care. Published 11 July 2023. doi:10.
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