Thyroid Function Testing During Pregnancy After Partial Thyroidectomy Versus the General Population: A Nationwide Retrospective Cohort
Authors' conclusion
Thyroid screening during pregnancy remains suboptimal. Pregnancies following partial thyroidectomy receive more frequent monitoring, suggesting recognition of their high-risk status. Findings highlight the need for better implementation of risk-based surveillance.
Study context
- Population
- Pregnancies 2002–2023 in women aged ≥18 years, Maccabi Healthcare Services databasematched cohort
- Exposure
- Pregnancies after partial thyroidectomy vs general population
- Partial thyroidectomyn = 718 pregnancies in 465
- General populationn = 929,022 pregnancies in 398,472reference
- Outcome
- Frequency of serum TSH measurements during pregnancy
- Follow-up
- During pregnancy
Methodological detailsnational, matched cohort
- National
- Matched cohort
Main finding
As reported in the abstract
TSH measured during pregnancy
P < 0.01
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Partial thyroidectomy | P value |
|---|---|---|
| Elevated TSH (prevalence) · pregnancySignificantly higher with partial thyroidectomy | 9% | P < 0.01 |
- Thyroid-stimulating hormone (TSH) testing across all 3 trimesters · pregnancy
- P < 0.01
TSH testing across all 3 trimesters · pregnancy
- Testing across all 3 trimesters differed between groups
Original publication
Thyroid Function Testing During Pregnancy After Partial Thyroidectomy Versus the General Population: A Nationwide Retrospective Cohort. Endocr Pract. Published 14 October 2025. doi:10.
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