Thyroid disease

Thyroid Dysfunction Following Thermal Ablation of Large Solid and Solid-Predominant Thyroid Nodules

Endocr PractPublished Prospective cohort study

Authors' conclusion

TA may cause short-term thyroid dysfunction, especially in patients with large TNs. Monitoring of thyroid hormone levels is recommended from 1 week to 3 months after TA to manage potential thyroid dysfunction effectively.

Study context

Population
Euthyroid patients with solid-predominant (≥ 80% solid) thyroid nodules treated with thermal ablation (microwave or radiofrequency)
Participants
77 patients
Outcome
Changes in thyroid hormones after thermal ablation (TA) and risk factors for thyroid dysfunction
Follow-up
1 week and 1, 3, 6, and 12 months after TA

Main finding

As reported in the abstract

Euthyroid rate after TA

Euthyroid rate at 1 week

70.1%

Euthyroid rate by 1 month

over 90%

Euthyroid rate by 12 months

100%

Observational data: associations, not effects.

Original publication

Thyroid Dysfunction Following Thermal Ablation of Large Solid and Solid-Predominant Thyroid Nodules. Endocr Pract. Published 22 January 2025. doi:10.1016/j.eprac.2025.01.004

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