Thyroid disease

Thyroid Arterial Embolization for the Management of Benign and Malignant Thyroid Disease: A Systematic Review

Endocr PractPublished Systematic review

Authors' conclusion

This review presents an overview of the literature regarding safety and efficacy of TAE. The lack of robust data, significant risk of serious complications (including nontarget embolization and mortality), and absence of a standardized, safe protocol preclude recommending TAE as a routine treatment option. Given the high efficacy and lower complication rates of current established therapies, TAE should only be considered in exceptional circumstances, when standard treatments have failed or are contraindicated, and then only at specialized centers with extensive embolization expertise.

Study context

Population
Studies of thyroid arterial embolization (TAE) for goiter, GD, thyrotoxicosis or thyroid malignancy; databases searched until January 202424 studies
Outcome
Safety and efficacy
Methodological detailsno meta-analysis, English-language studies
  • No meta-analysis
  • English-language studies

Pooled result

As reported in the abstract

Studies by indication: goiter

8 studies

Studies by indication: GD

8

Studies by indication: thyroid malignancy

5

Studies by indication: thyrotoxicosis

4

Safety

Minimal complications like neck pain and hematoma
Serious risks, incl. nontarget embolization and mortality, require caution

Original publication

Thyroid Arterial Embolization for the Management of Benign and Malignant Thyroid Disease: A Systematic Review. Endocr Pract. Published 6 August 2025. doi:10.1016/j.eprac.2025.07.024

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