The use of dietary supplements, and the association between supplemental vitamin D and glycaemic control in adult individuals with type 1 diabetes
Authors' conclusion
Supplement use was frequent in this sample of adult individuals with type 1 diabetes. Due to potential drug-supplement interactions, the attending physicians should be aware of their patients' supplement use. The causality between vitamin D supplementation and glycaemic control should be assessed in a randomized controlled trial.
Study context
- Population
- Adults with T1D and eGFR ≥60 mL/min/1.73 m² who completed a diet questionnaire, Finnish Diabetic Nephropathy Study; 43% men, mean ± SD age 45 ± 13 years
- Participants
- 1,181 adults
- Exposure
- Vitamin D supplementation vs no vitamin D supplementation
- Outcome
- Dietary supplement use (past 30 days)
Methodological detailsobservational
- Observational
Main finding
As reported in the abstract
- Any supplement use
- 62%
- Some vitamin or mineral supplement use
- 56%
- Non-vitamin and non-mineral supplement use
- 27%
- Vitamin D supplement use
- 45%
- Magnesium supplement use
- 31%
Observational data: associations, not effects.
Further findings
- Daily dose 30 μg vs none: B (Wald CI), p
- −2.76 [−5.03 to −0.49], 0.017
- Vitamin D supplementation associated with better glycaemic control (multivariable models)
- Evidence of improving glycaemic control with higher doses from a daily dose of ≥30 μg
Original publication
The use of dietary supplements, and the association between supplemental vitamin D and glycaemic control in adult individuals with type 1 diabetes. Diabet Med. Published 14 February 2024. doi:10.
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