The MiniMed 780G automated insulin delivery system adapts to substantial changes in daily routine: Lessons from real world users during Ramadan
Authors' conclusion
The MiniMed 780G automated insulin delivery system is effective, safe and fast in adapting to the substantial changes that occur in the lifestyle of people with type 1 diabetes during Ramadan.
Study context
- Population
- MiniMed 780G AID users from the Gulf region with ≥10 days of sensor glucose data during Ramadan 2022 and in the month before and after
- Participants
- 449 participants
- Exposure
- Ramadan vs month before
- Outcome
- CGM endpoints aggregated per month, reported by time of day (daytime: 05.31-18.00 h, and night-time)
- Follow-up
- Ramadan 2022
Methodological detailsreal-world CareLink Personal data, Gulf region
- Real-world CareLink Personal data
- Gulf region
Main finding
As reported in the abstract
Glycaemic control during Ramadan
- Mean sensor glucose (mean ± SD)
- 152.6 ± 18.7 mg/dl
- GMI (mean ± SD)
- 7.0 ± 0.4%
- TIR (mean ± SD)
- 70.7 ± 11.0%
- Time below 70 mg/dl (mean ± SD)
- 2.3 ± 2.3%
- Some metrics differed from the month before, but absolute differences were very small and considered clinically irrelevant
- p < .0001 for all
Observational data: associations, not effects.
Further findings
TIR by time of day during Ramadan
- Daytime TIR (highest)
- 80.0 ± 10.7%
- Night-time TIR
- 60.4 ± 15.3%
Time above 180 mg/dl by time of day during Ramadan
- Night-time TAR >180 mg/dl (highest)
- 37.3 ± 16.3%
- Daytime TAR >180 mg/dl
- 17.7 ± 10.7%
Algorithm adaptation
- The algorithm adapted immediately upon lifestyle change
Safety
Daytime hypoglycaemia during Ramadan
- No increased risk of hypoglycaemia during daytime; daytime time below 70 mg/dl
- 2.3 ± 2.4%
Original publication
The MiniMed 780G automated insulin delivery system adapts to substantial changes in daily routine: Lessons from real world users during Ramadan. Diabetes Obes Metab. Published 27 December 2023. doi:10.
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