The Influence of Ultraprocessed Food Consumption on Energy Intake in Emerging Adulthood: A Controlled Feeding Trial

Obesity (Silver Spring)Published Randomised crossover trial

Authors' conclusion

Late adolescents may be susceptible to increased EI following a UPF diet. Future trials are warranted to evaluate this possibility.

Study context

Population
Individuals aged 18–25; mean age 22 ± 2 years, mean BMI 24 ± 3 kg/m²crossover
Participants
27 individuals
Comparison
81% ultraprocessed foods (UPF) diet vs 0% UPF diet for 14 days each
Primary endpoint
Ad libitum energy intake (EI) and food selection at a buffet meal
Follow-up
After each 14-day diet
Methodological detailsrandomized, proof-of-concept, controlled feeding, 4-week washout, Diet compliance ≈99% overall, Diets matched for macronutrients, fiber, added sugar, diet quality and energy density
  • Randomized
  • Proof-of-concept
  • Controlled feeding
  • 4-week washout
  • Diet compliance ≈99% overall
  • Diets matched for macronutrients, fiber, added sugar, diet quality and energy density

Primary result

As reported in the abstract

Buffet meal total kcal, grams, UPF and non-UPF consumption (full sample)
  • No effect of diet condition on meal total kcal or grams consumed or UPF or non-UPF consumption
  • UPF vs non-UPF: all p > 0.05

Further findings

OutcomeCohen's dP value
Total EI by age subgroup (exploratory)UPF vs non-UPF · interaction between diet and age · exploratory age subgroup analysisP < 0.001 for diet × age interaction
Total EI by age subgroup (exploratory)UPF vs non-UPF · late adolescents (18-21): total EI increased after UPF diet · exploratory age subgroup analysis0.79P = 0.03

Total energy intake (EI) by age subgroup (exploratory)

Young adults (22-25): no increase in total EI after UPF diet

Original publication

The Influence of Ultraprocessed Food Consumption on Energy Intake in Emerging Adulthood: A Controlled Feeding Trial. Obesity (Silver Spring). Published 19 November 2025. doi:10.1002/oby.70086

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