Pediatric endocrinology

The Individual Relationship between Pubertal Growth and Physical Changes of Puberty in Healthy Adolescents

Horm Res PaediatrPublished Longitudinal cohort study

Authors' conclusion

We found that the magnitude of the pubertal growth spurt was linked with the age at reaching Tanner landmarks of puberty in girls and boys; however, there was no association between the timing of these landmarks and AH. This new knowledge can provide reassurance for healthy children that the normal variation of pubertal timing does not have a significant influence on expected AH.

Study context

Population
Healthy children born 1972–1976 with birth weight >2.5 kg, Edinburgh growth studyincluded in analysis
Participants
157 children
Exposure
Boys vs Girls
  • Boysn = 89
  • Girlsn = 68
Outcome
Correlation of age at Tanner stages with total pubertal growth (TPG) and adult height (AH)
Methodological detailslongitudinal growth study, Anthropometry and Tanner staging twice a year; Total pubertal growth (TPG) quantified with QEPS growth model
  • Longitudinal growth study
  • Anthropometry and Tanner staging twice a year; TPG quantified with QEPS growth model

Main finding

As reported in the abstract

Girls: correlation coefficient B3 vs TPG

−0.64

p < 0.01

Girls: correlation B3 vs adult height (AH), no correlation

0.15

p = 0.24

Boys: correlation G4 vs TPG

−0.24

p < 0.04

Boys: correlation G4 vs AH, not correlated

0.02

p = 0.86

Observational data: associations, not effects.

Original publication

The Individual Relationship between Pubertal Growth and Physical Changes of Puberty in Healthy Adolescents. Horm Res Paediatr. Published 24 December 2025. doi:10.1159/000550225

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