The impact of direct oral anticoagulants on hip fracture care in Australia and New Zealand: a prospective patient sprint audit
Authors' conclusion
Patients on DOACs are likely to experience delays to surgery compared to patients on no antithrombotic medication, beyond what patients on other antithrombotic medications may experience.
Study context
- Population
- Patients aged ≥ 50 years admitted with hip fracture, and New Zealand Hip Fracture Registry (ANZHFR) hospitals, Australia and New Zealand, 1 June–30 July 2024
- Participants
- 1,043 patients
- Exposure
- Direct oral anticoagulants (DOACs) vs other antithrombotic medication vs no antithrombotic medication
- DOACsn = 192
- Outcome
- Time to surgery
Methodological detailssprint audit, consecutive patients, multicentre (ANZHFR hospitals)
- Sprint audit
- Consecutive patients
- Multicentre (ANZHFR hospitals)
Main finding
As reported in the abstract
Time to surgery > 36 h; median time to surgery
Each group vs no antithrombotic medicationOdds ratio (95% CI)
DOACs
3.65(2.40–5.55)
Other antithrombotic medication
1.62(1.12–2.34)
Observational data: associations, not effects.
Safety
- No differences in the proportion of patients who had perioperative blood transfusions
Original publication
The impact of direct oral anticoagulants on hip fracture care in Australia and New Zealand: a prospective patient sprint audit. Osteoporos Int. Published 19 August 2025. doi:10.
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