The impact of diabetes mellitus on foot perfusion measured by ICG NIR fluorescence imaging
Authors' conclusion
DM is associated with increased in- and outflow parameters. Patients with- and without DM should not be compared directly due to different vascular pathophysiology and multifactorial wound problems in DM patients. Quantified ICG NIR fluorescence imaging offers additional insight into the effect of DM on foot perfusion.
Study context
- Population
- Patients with lower extremity arterial disease (LEAD) undergoing baseline ICG NIR fluorescence imaging of the foot122 limbs
- Participants
- 109 patients
- Exposure
- LEAD patients with Diabetes Mellitus (DM) vs without DM
- Outcome
- Ten ICG NIR foot perfusion parameters
- Follow-up
- Baseline
Main finding
As reported in the abstract
Proportion of patients with DM
32.8 %
Perfusion parameters differing significantly between DM and non-DM
6 of 10
Observational data: associations, not effects.
Further findings
Perfusion parameters in Fontaine stage 4
- Fontaine stage 4 DM patients had the highest in- and outflow values; parameters significantly higher (p-values 0.004-0.035)
- 7
Original publication
The impact of diabetes mellitus on foot perfusion measured by ICG NIR fluorescence imaging. Diabetes Res Clin Pract. Published 6 July 2024. doi:10.
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