The Human Fecal Endocannabinoidome Mediator Profile Is Mainly Defined by the Fecal Microbiota and Diet
Authors' conclusion
The fecal eCBome profile is associated with gut microbiota composition and dietary intakes, more than with the circulating profile. These results strengthen the hypothesis of an interrelation between the gut microbiome and eCBome signaling involved in the regulation of numerous host biological processes.
Study context
- Population
- Human adults with plasma and feces profiled, comprehensive dietary intake and gut microbiota measurescohort n = 195
- Outcome
- Fecal eCBome mediator profile (NAEs and 2-MAGs)
Methodological detailswith short-term dietary intervention trial
- With short-term dietary intervention trial
Main finding
As reported in the abstract
N-acyl-ethanolamines (NAEs) identified in fecal samples
6
2-MAGs identified in fecal samples
7
Observational data: associations, not effects.
Original publication
The Human Fecal Endocannabinoidome Mediator Profile Is Mainly Defined by the Fecal Microbiota and Diet. J Clin Endocrinol Metab. Published 22 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →