The global macroeconomic burden of diabetes mellitus
Authors' conclusion
These findings highlight the uneven distribution of diabetes' economic impact
Study context
- Population
- 204 countries and territories, 2020–2050204 countries and territories
- Outcome
- Economic impact of DM: losses in effective labor supply due to mortality and morbidity, treatment-related resource diversion and informal caregiving costs
- Follow-up
- 2020 to 2050
Methodological detailshealth-augmented macroeconomic model, 204 countries and territories
- Health-augmented macroeconomic model
- 204 countries and territories
Main finding
As reported in the abstract
Global macroeconomic burden of DM
Global burden without informal care (2017 INT$)
$10.2 trillion
Burden without informal care as share of annual global GDP
0.22%
Global burden including informal care
INT$78.8 trillion
Range including informal care, depending on care assumptions
INT$5.5 trillion to INT$152.1 trillion
Further findings
Distribution of burden by country
- Absolute costs highest in the United States, China and India
- Relative and per capita burdens greatest in countries such as American Samoa and Australia
Original publication
The global macroeconomic burden of diabetes mellitus. Nat Med. Published 29 December 2025. doi:10. 1038/ s41591-025-04027-5
Composed by AI from the published abstract and checked against it. How Briefs are made →