Type 2 & other diabetes

The global macroeconomic burden of diabetes mellitus

Nat MedPublished Macroeconomic modelling study

Authors' conclusion

These findings highlight the uneven distribution of diabetes' economic impact

Study context

Population
204 countries and territories, 2020–2050204 countries and territories
Outcome
Economic impact of DM: losses in effective labor supply due to mortality and morbidity, treatment-related resource diversion and informal caregiving costs
Follow-up
2020 to 2050
Methodological detailshealth-augmented macroeconomic model, 204 countries and territories
  • Health-augmented macroeconomic model
  • 204 countries and territories

Main finding

As reported in the abstract

Global macroeconomic burden of DM

Global burden without informal care (2017 INT$)

$10.2 trillion

Burden without informal care as share of annual global GDP

0.22%

Global burden including informal care

INT$78.8 trillion

Range including informal care, depending on care assumptions

INT$5.5 trillion to INT$152.1 trillion

Further findings

Distribution of burden by country

Absolute costs highest in the United States, China and India
Relative and per capita burdens greatest in countries such as American Samoa and Australia

Original publication

The global macroeconomic burden of diabetes mellitus. Nat Med. Published 29 December 2025. doi:10.1038/s41591-025-04027-5

Composed by AI from the published abstract and checked against it. How Briefs are made →

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