Global, regional, and national cascades of diabetes care, 2000–23: a systematic review and modelling analysis using findings from the Global Burden of Disease Study
Authors' conclusion
Despite improvements over the past two decades, underdiagnosis and suboptimal glycaemic management of diabetes remain major challenges globally, particularly in low-income and middle-income countries. These findings highlight the urgent need for enhanced strategies and capacity building to improve the detection, treatment, and management of diabetes worldwide. Targeted interventions to bolster health-care systems' capacity to effectively diagnose and manage diabetes could lead to better health outcomes and reduce the burden of this growing disease.
Study context
- Population
- People with diabetes aged 15 years and older, 204 countries and territories, 2000–2023
- Outcome
- Diabetes cascade of care: proportion diagnosed among those with diabetes, proportion treated among those diagnosed, proportion with optimal glycaemic concentrations among those treated
- Follow-up
- 2023
Methodological detailsGlobal Burden of Disease Study, hierarchical Bayesian meta-regression (DisMod-MR 2.1), 204 countries and territories, 2000–2023
- Global Burden of Disease Study
- Hierarchical Bayesian meta-regression (DisMod-MR 2.1)
- 204 countries and territories
- 2000–2023
Pooled result
As reported in the abstract
Diagnosed among people with diabetes aged ≥15 years
55.8%
95% UI 49.3–62.3
On treatment among those diagnosed
91.4%
88.0–94.2
Optimal glycaemic concentrations among those on treatment
41.6%
35.7–48.5
Optimal glycaemic concentrations on treatment among all people with diabetes
21.2%
17.4–25.6
Further pooled results
Change in cascade, globally · 2000 to 2023
- Increase in proportion diagnosed (percentage points)
- 8.3 (6.6-10.0)
- Increase in proportion treated among diagnosed (percentage points)
- 7.2 (5.7-8.8)
- Increase in optimal glycaemic concentrations among treated (percentage points)
- 1.3 (0.8-1.8)
Regional differences · 2023
- Highest diagnosis in high-income North America, highest treatment among diagnosed in high-income Asia Pacific, highest optimal glycaemic concentrations among treated in southern Latin America
Original publication
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