The effect of preprandial versus postprandial physical activity on glycaemia: Meta-analysis of human intervention studies

Diabetes Res Clin PractPublished Systematic review and meta-analysis of intervention studies

An erratum to this article was published (Diabetes Res Clin Pract, Mar 2026 ↗)

Pooled result · Glucose AUC during glucose tolerance test (RCTs)Result — go to the resultPooled mean difference −0.29 mmol/L 95 % CI −0.66 to 0.08

Authors' conclusion

In conclusion, we found no differences between preprandial PA versus postprandial PA on glycaemia both after one PA bout as well as after multiple weeks of PA.

Study context

Population
Adults in human intervention studies directly comparing preprandial vs postprandial physical activity (PA) on glycaemia; Medline and Embase.com searched until February 202328 studies
Comparison
Preprandial PA vs postprandial PA
Outcome
Glucose AUC during glucose tolerance test (RCTs)
Follow-up
Multiple weeks
Methodological detailsrandom-effects models, pooled mean differences, Low to moderate quality of evidence (GRADE), Screened with ASReview (34,837); 42 full texts read by two independent reviewers, 28 included
  • Random-effects models
  • Pooled mean differences
  • Low to moderate quality of evidence (GRADE)
  • Screened with ASReview (34,837); 42 full texts read by two independent reviewers, 28 included

Pooled result

As reported in the abstract

Pooled mean difference

−0.29 mmol/L

95 % CI −0.66 to 0.08

Preprandial PAvs Postprandial PA
pooled mean difference −0.29 mmol/L (95 % CI −0.66 to 0.08)

Further pooled results

Acute response studies (21 studies) · 24 h

Postprandial outcomes followed expected physiological patterns; outcomes measured over 24 h showed no significant differences

Subgroup analyses (quality, health status, etc.)

Did not significantly change the outcomes

Original publication

The effect of preprandial versus postprandial physical activity on glycaemia: Meta-analysis of human intervention studies. Diabetes Res Clin Pract. Published 27 March 2024. doi:10.1016/j.diabres.2024.111638

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.