The effect of frailty on post-discharge management and outcomes of acute glycaemic crises: Analysis of admissions for hypoglycaemia and hyperglycaemia in Australia
Authors' conclusion
Frailty was associated with more conservative diabetes medication management following hypoglycaemia and hyperglycaemia admissions.
Study context
- Population
- People with probable T2D in Victoria, Australia, admitted to hospital for hypoglycaemia or hyperglycaemia, 1 July 2013–29 June 20172,506 hypo + 1,693 hyper admissions
- Exposure
- Glucose-lowering drug (GLD) dispensing in the year before vs after admission, by frailty status
- Outcome
- Change in mean annual GLD dispensing count, year before vs after admission, by frailty status
- Follow-up
- Year before and after admission
Methodological detailspopulation-based, linear regression adjusted for age, sex, comorbidities and socioeconomic status
- Population-based
- Linear regression adjusted for age, sex, comorbidities and socioeconomic status
Main finding
As reported in the abstract
Change in mean annual GLD dispensing count after hypoglycaemia admission · year after vs year before admission
Hospital Frailty Risk Score (HFRS) 15
−4.11
mean · CI −5.05–-3.17 · dispensings/year
HFRS 0
−0.99
mean · CI −1.47–-0.50 · dispensings/year
Observational data: associations, not effects.
Further findings
Mean, dispensings/year
| Outcome | HFRS 0 | HFRS 15 |
|---|---|---|
| Change in mean annual GLD dispensing count after hyperglycaemia admission · year after vs year before admission | 2.44 (CI 1.32–3.56) | 1.16 (CI 0.18–2.14) |
Change in mean annual GLD dispensing count after hyperglycaemia admission · year after vs year before admission
- Mean annual GLD dispensings increased, with a smaller increase with increasing frailty
Original publication
The effect of frailty on post-discharge management and outcomes of acute glycaemic crises: Analysis of admissions for hypoglycaemia and hyperglycaemia in Australia. Diabetes Res Clin Pract. Published 9 February 2024. doi:10.
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