The Cancer-Specific Health Economic Measure QLU-C10D is Valid and Responsive for Assessing Health Utility in Patients with Thyroid Cancer
Authors' conclusion
The QLU-C10D is a valid PBM for health economic evaluations in thyroid cancer studies.
Study context
- Population
- Patients with differentiated, medullary or anaplastic thyroid cancer from nine countries (three continents)analyzable data
- Participants
- 181 patients
- Exposure
- QLU-C10D vs EQ-5D-5L
- Outcome
- Validity and responsiveness of QLU-C10D
Methodological detailspsychometric validation, multicenter, multinational, longitudinal
- Psychometric validation
- Multicenter
- Multinational
- Longitudinal
Main finding
As reported in the abstract
Intra-class correlation of EQ-5D-5L and QLU-C10D index values across timepoints (criterion validity)
0.761 to 0.901
Spearman's correlation for theoretically corresponding domain pairs
0.289 to 0.716
Known-group comparisons with differences detected by QLU-C10D
9 of 15
QLU-C10D higher statistical efficiency than EQ-5D-5L
74.7% of comparisons
Observational data: associations, not effects.
Original publication
The Cancer-Specific Health Economic Measure QLU-C10D is Valid and Responsive for Assessing Health Utility in Patients with Thyroid Cancer. Thyroid. Published 30 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →