Core Outcome Set of the Surgical Treatment of Differentiated Thyroid Carcinoma: International Consensus by Delphi Study
Authors' conclusion
This international consensus on the COS for DTC surgery promotes consistent and appropriate outcome selection in clinical practice and research and may be incorporated into future study designs.
Study context
- Population
- Experts and patient representatives from 35 countries across 5 continents; development of a core outcome set for surgical treatment of differentiated thyroid cancer (DTC)125 experts · 7 patient representatives
- Outcome
- Consensus on outcomes for inclusion in the DTC surgical core outcome set:
- Consensus-in: ≥70% of both stakeholder groups rating 7-9
- 90% in one group
Methodological detailsinternational, two-round Delphi, literature review, expert panel meeting, Steering committee incl. a patient representative from the Dutch Thyroid Patient Organization advised on protocol, Delphi rounds and panel meeting
- International
- Two-round Delphi
- Literature review
- Expert panel meeting
- Steering committee incl. a patient representative from the Dutch Thyroid Patient Organization advised on protocol, Delphi rounds and panel meeting
Recommendations
As reported in the abstract
Outcomes reaching consensus after two rounds
17
Outcomes ratified at expert panel meeting: recurrence, persistent disease, location of metastatic lymph nodes, number of retrieved metastatic lymph nodes, postoperative Tg levels, surgical completeness, permanent recurrent laryngeal nerve paralysis due to surgery, permanent postoperative hypoparathyroidism, 30-day postoperative complication rate, accidental intraoperative injury to adjacent organ, unplanned reoperation rate, 30-day postoperative mortality, quality of life
13
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →