Endocrine oncology

Dynamic risk stratification in patients with follicular thyroid carcinoma treated with lobectomy

Eur Thyroid JPublished Cohort study

Authors' conclusion

Long-term follow-up may be needed in FTC patients treated with lobectomy alone even though they had an excellent response to initial thyroid surgery, especially in patients with a higher risk of recurrence.

Study context

Population
Patients with follicular thyroid carcinoma (FTC) diagnosed January 2005–December 2014 who underwent lobectomy alone
Participants
161 patients
Exposure
Excellent response vs structural-incomplete response by dynamic risk stratification (DRS)
  • Excellent responsen = 159reference
  • Structural-incomplete responsen = 2
Outcome
DFS by DRS category
Follow-up
10 years

Main finding

As reported in the abstract

DFS

P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeExcellent responseStructural-incomplete responseP value
DFS, subgroup VI ≥ 2 (n = 54) · 10 years83.2% · n = 530% · n = 1P < 0.001
Disease-free survival (DFS), subgroup VI ≥ 2 (n = 54) — Recurrence among 53 excellent responders
10 patients
DFS, subgroup VI ≥ 2 (n = 54) — Time from surgery to recurrence 2-5 years
1
DFS, subgroup VI ≥ 2 (n = 54) — Time from surgery to recurrence 5-8 years
2
DFS, subgroup VI ≥ 2 (n = 54) — Time from surgery to recurrence 8-10 years
4
DFS, subgroup VI ≥ 2 (n = 54) — Time from surgery to recurrence 10 years or more
3

Original publication

Dynamic risk stratification in patients with follicular thyroid carcinoma treated with lobectomy. Eur Thyroid J. Published 5 November 2025. doi:10.1530/etj-25-0154

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