The burden of diabetic foot ulcers in a multi‐ethnic Asian cohort
Authors' conclusion
DFU represent a substantial clinical burden in Singapore and are independently associated with adverse outcomes. Beyond preventive screening, early multidisciplinary, multi-specialty management is critical to reduce amputations, hospitalization, and hence mortality.
Study context
- Population
- Patients aged ≥18 years with diabetes mellitus (DM), SingHealth Diabetes Registry, tertiary centre, August 2018–December 2023analysed
- Participants
- 22,830 patients
- Exposure
- DFU vs no DFU; DREAM clinic referral vs no referral within DFU cohort
- DFUn = 2,527
- Outcome
- DFU burden and outcomes
Methodological detailsregistry-based, single tertiary centre
- Registry-based
- Single tertiary centre
Main finding
As reported in the abstract
DFU
11.1%
2527
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Demographic and comorbidity profile | P < 0.001 |
- Demographic and comorbidity profile: higher prevalence of cardiovascular and metabolic comorbidities with DFU
Demographic and comorbidity profile
- Individuals with DFU were older and had longer DM duration
LEA within DFU cohort: DREAM clinic referral (subgroup)
- DREAM clinic referral independently associated with significantly reduced risk of major LEA after multivariable adjustment
- No association with minor LEA
Original publication
The burden of diabetic foot ulcers in a multi‐ethnic Asian cohort. Diabet Med. Published 24 April 2026. doi:10.
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