Temporal trends in socioeconomic inequalities and risk of infection after hip fracture surgery: a nationwide cohort study, 2010–2021
Authors' conclusion
Our results indicate growing inequality in health among patients with hip fracture, whereby lower education, lack of social support, and reliance on residential care represent increasing disadvantages for infection risk.
Study context
- Population
- Patients with hip fracture undergoing surgery, Danish population-based registries, 2010–2021
- Participants
- 74,068 patients
- Exposure
- Socioeconomic position markers across four calendar periods, 2010–2021
- Outcome
- Any hospital-treated or community-treated infection after surgery; inequality measured by adjusted SII (hazard difference/100 person years) and adjusted RII (relative hazard)
- Follow-up
- 30 days after surgery
Methodological detailspopulation-based registries, additive hazard regression, Cox proportional hazard regression
- Population-based registries
- Additive hazard regression
- Cox proportional hazard regression
Main finding
As reported in the abstract
Inequality in hospital-treated infections, 2010 vs 2021 · 30 days
- Education, 2010: Slope index of inequality (SII)
- 14 [- 20; 49]
- Education, 2010: Relative index of inequality (RII)
- 1.1 [0.9; 1.3]
- Education, 2021: SII
- 36 [0; 71]
- Education, 2021: RII
- 1.2 [1; 1.3]
- Marital status, 2010: SII
- 29 [- 9; 66]
- Marital status, 2010: RII
- 1.2 [1; 1.4]
- Marital status, 2021: SII
- 84 [45; 123]
- Marital status, 2021: RII
- 1.4 [1.2; 1.7]
- Living arrangements, 2010: SII
- - 32 [- 78; 14]
- Living arrangements, 2010: RII
- 0.9 [0.7; 1.1]
- Living arrangements, 2021: SII
- 106 [59; 153]
- Living arrangements, 2021: RII
- 1.5 [1.3; 1.8]
Observational data: associations, not effects.
Further findings
Incidence of hospital-treated infections · 30 days
- Total patients with hospital-treated infection
- 12,654
- Range by calendar period and socioeconomic position
- 14 and 21%
Incidence of community-treated infections · 30 days
- Total patients with community-treated infection
- 20,523
- Range by calendar period and socioeconomic position
- 21 and 38%
Inequality in community-treated infections · 30 days
- Similar trends observed as for hospital-treated infections
Original publication
Temporal trends in socioeconomic inequalities and risk of infection after hip fracture surgery: a nationwide cohort study, 2010–2021. Osteoporos Int. Published 23 June 2025. doi:10. 1007/ s00198-025-07576-0
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