Temporal incremental healthcare costs associated with complications in Hong Kong Chinese patients with type 2 diabetes: A prospective study in Joint Asia diabetes evaluation (JADE) Register (2007–2019)
Authors' conclusion
These comprehensive temporal healthcare cost estimates for diabetes-related complications allows the performance of long-term, patient-level, cost-effectiveness analyses on T2D prevention and treatment strategies relevant to an Asian and possibly global contexts. These may inform decision-makers on resource allocation aimed at reducing the burden of T2D and chronic diseases.
Study context
- Population
- Hong Kong Chinese patients with T2D, JADE Register, 2007–2019; mean ± SD age 59.9 ± 11.9 years, 56.6 % men, diabetes duration 7.3 ± 7.5 years, HbA1c 7.5 ± 1.6 %
- Participants
- 19,440 patients142,132 patient-years
- Outcome
- Incremental healthcare costs (inpatient and outpatient) associated with nine non-fatal diabetes complications and all-cause death
- Follow-up
- Year of occurrence and post-event years
Methodological detailsregistry-based (JADE Register), two-part model, adjusted for demographic, clinical, lifestyle factors and comorbidities
- Registry-based (JADE Register)
- Two-part model
- Adjusted for demographic, clinical, lifestyle factors and comorbidities
Main finding
As reported in the abstract
Lower extremity amputation (LEA), 95% CI 25,706-37,004
USD$31,302
Hemorrhagic stroke, CI 17,680-24,626
USD$21,164
Ischemic stroke, CI $15,937-20,352
USD$17,976
ESRD, CI 13,405-16,250
USD$14,774
Observational data: associations, not effects.
Further findings
Mean annual healthcare costs, mainly due to inpatient cost · follow-up 7 (IQR 4-9) years
- Mean ± SD annual healthcare costs
- USD$2,990 ± 9,960
Residual healthcare costs in post-event years
- Highest for ESRD, LEA, haemorrhagic stroke and incident cancer
Original publication
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