Suicide Attempts After a Diagnosis of Polycystic Ovary Syndrome : A Cohort Study
Main finding · Suicide attemptResult — go to the resultHazard ratio 8.47 95% CI 7.54–9.51Authors' conclusion
This study underscores the heightened risk for suicide attempt that persons with PCOS face, even after adjustment for demographics, psychiatric comorbid conditions, physical conditions, and all-cause clinical visits. This suggests the importance of routine monitoring of mental health and suicide risk in persons diagnosed with PCOS.
Study context
- Population
- Persons with PCOS and matched controls, Taiwanese nationwide database, 1997–2012matched cohort
- Exposure
- PCOS vs matched controls
- PCOSn = 18,960
- Outcome
- Suicide attempt
Methodological detailsnationwide, matched 1:10 on age, psychiatric comorbid conditions, urbanization level and income, Cox regression
- Nationwide
- Matched 1:10 on age, psychiatric comorbid conditions, urbanization level and income
- Cox regression
Main finding
As reported in the abstract
Hazard ratio
8.47
95% CI 7.54–9.51
PCOSvs Control
HR 8.47 (95% CI 7.54–9.51)
Observational data: associations, not effects.
Further findings
| Outcome | HR (CI) | |
|---|---|---|
| Suicide attempt by age groupPCOSvs ControlAdolescent | 5.38 (3.93–7.37) | |
| Suicide attempt by age groupPCOSvs ControlYoung adult (<40 years) | 9.15 (8.03–10.42) | |
| Suicide attempt by age groupPCOSvs ControlOlder adult | 3.75 (2.23–6.28) | |
| 0.050.21520Hazard ratio (log scale) |
Sensitivity analyses
- Excluding the first year or first 3 years of observation yielded consistent results
Original publication
Suicide Attempts After a Diagnosis of Polycystic Ovary Syndrome : A Cohort Study. Ann Intern Med. Published 6 February 2024. doi:10.
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