Type 1 diabetes

Suicidal Ideation, Suicide Attempts, and Suicide Deaths in Adolescents and Young Adults With Type 1 Diabetes: A Systematic Review and Meta-analysis

Diabetes CarePublished Systematic review and meta-analysis of observational studies

Authors' conclusion

Suicidal ideation and suicide attempts are prevalent in AYA with T1D. Current evidence does not suggest that these rates are higher among AYA with T1D than rates among those without.

Study context

Population
Adolescents and young adults (AYA) aged 10–24 years with T1D; MEDLINE, Embase and PsycInfo searched up to 3 September 202331 studies
Comparison
AYA with T1D vs without T1D
Outcome
Prevalence of suicidal ideation, suicide attempts and suicide deaths in AYA with T1D

Pooled result

As reported in the abstract

Pooled prevalence of suicidal ideation
GroupValueStudies
T1D15.4% (95% CI 10.0–21.7)18
Without T1D11.5% (CI 0.4–33.3)4

Value

T1D15.4% (95% CI 10.0–21.7)
Without T1D11.5% (CI 0.4–33.3)

Studies

T1D18
Without T1D4

Further pooled results

OutcomeT1DWithout T1D
Pooled prevalence of suicide attemptsConsiderable heterogeneity3.5% (CI 1.3–6.7)2.0% (CI 0.0–6.4)
Studies85

Prevalence of suicide deaths in youth with T1D

Prevalence of suicide deaths ranged
0.04% to 4.4%

Factors associated with suicide-related behaviors

Difficulties with T1D self-management frequently reported as associated with higher rates of suicide-related behaviors
Findings on association of glycemic levels with suicide-related behaviors were inconsistent

Original publication

Suicidal Ideation, Suicide Attempts, and Suicide Deaths in Adolescents and Young Adults With Type 1 Diabetes: A Systematic Review and Meta-analysis. Diabetes Care. Published 20 June 2024. doi:10.2337/dc24-0411

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