Success Rate and Safety of Adrenal Venous Sampling via the Antecubital Approach: A Systematic Review and Meta-Analysis
Pooled result · Right adrenal vein cannulation success rateResult — go to the resultOR for successful cannulation 1.43 95% CI 0.23–9.04Authors' conclusion
Antecubital AVS demonstrated acceptable success rates and safety, particularly in moderate- to high-volume centers, without clear inferiority to the femoral approach.
Study context
- Population
- Patients with primary aldosteronism undergoing adrenal venous sampling (AVS)
- Participants
- 2,332 patients11 studies
- Comparison
- Antecubital vs femoral approach for AVS
- Outcome
- Success rate of right and left adrenal vein cannulation
Methodological detailsSearched PubMed, Embase, Cochrane Library, Web of Science and Wanfang Data from inception to May 1, 2025
- Searched PubMed, Embase, Cochrane Library, Web of Science and Wanfang Data from inception to May 1, 2025
Pooled result
Right adrenal vein cannulation success rate
OR for successful cannulation
1.43
95% CI 0.23–9.04
By group
Antecubital
91.9%
single-arm pooled estimate · 95% CI 85.26%–95.70%
Antecubitalvs Femoral
OR for successful cannulation 1.43 (95% CI 0.23–9.04)
As reported in the abstract
Further pooled results
| Outcome | Antecubital | OR for successful cannulation (95% CI) | |
|---|---|---|---|
| Left adrenal vein cannulation success rate (primary outcome) | single-arm pooled estimate 95.35% (95% CI 94.34%–96.19%) | 1.44 (0.63–3.28) | |
| 0.20.5125OR for successful cannulation (log scale) |
| Outcome | Antecubital | WMD (minutes) (95% CI) | |
|---|---|---|---|
| Fluoroscopy time | single-arm pooled estimate 7.64 (95% CI 6.12–9.16) minutes | 0.62 (−0.75 to 1.99) | |
| −1012Difference, minutes (linear scale) |
| Outcome | Antecubital | WMD (mL) (95% CI) | |
|---|---|---|---|
| Contrast agent volume | single-arm pooled estimate 19.37 (95% CI 15.9–22.83) mL | 0.19 (−0.57 to 0.96) | |
| −1−0.500.51Difference, mL (linear scale) |
Safety
| Outcome | Antecubital | OR (95% CI) | |
|---|---|---|---|
| Procedure-related complications | 0.36% (95% CI 0.07%–0.79%) | 0.51 (0.17–1.60) | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Success Rate and Safety of Adrenal Venous Sampling via the Antecubital Approach: A Systematic Review and Meta-Analysis. Endocr Pract. Published 30 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →