Adrenal Venous Sampling Via an Antecubital Approach in Primary Aldosteronism: A Multicenter Study
Authors' conclusion
This multicenter study demonstrates that AVS via an antecubital approach is safe and feasible, with a high rate of successful sampling, which may be an alternative to the femoral vein access method.
Study context
- Population
- Patients with PA who underwent adrenal venous sampling (AVS) via an antecubital approach, 7 Chinese medical centers, January 2012–December 2018; mean age 47.1 years, 57.9% male
- Participants
- 1,226 patients
- Outcome
- Success rate of AVS via an antecubital approach (selectivity index >2)
Methodological detailsmulticenter, 7 Chinese medical centers
- Multicenter
- 7 Chinese medical centers
Main finding
As reported in the abstract
Sampling success rate
Bilateral sampling success
91.5%
Right sampling success
94.9%
Left sampling success
95.1%
Observational data: associations, not effects.
Further findings
Success rate, initial 70 cases vs subsequent cases
- Bilateral: initial 70 cases vs subsequent
- 82.9% vs 92.0% (P = .012)
- Right: initial 70 cases vs subsequent
- 87.1% vs 95.3% (P = .008)
- Left: initial 70 cases vs subsequent
- 88.6% vs 95.5% (P = .018)
- Initial 70 cases = initial 10 cases at each center
Puncture site and access change
- Right antecubital vein
- 1211 (98.8%)
- Left antecubital vein
- 15 (1.2%)
- Changed to right femoral vein (cannulation failure or adrenal vein anatomic variation)
- 6 (0.5%)
Safety
- Adrenal vein rupture, no sequelae
- 5 patients (0.41%)
Original publication
Adrenal Venous Sampling Via an Antecubital Approach in Primary Aldosteronism: A Multicenter Study. J Clin Endocrinol Metab. Published 19 July 2023. doi:10. 1210/ clinem/ dgad433
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