Gestational diabetes & diabetes in pregnancy
Subtypes of Gestational Diabetes Mellitus Are Differentially Associated With Newborn and Childhood Metabolic Outcomes
Authors' conclusion
GDM subtypes are differentially associated with newborn and childhood outcomes. Better characterizing individuals with GDM could help identify at-risk offspring to offer targeted, preventative interventions early in life.
Study context
- Population
- Mother-offspring dyads in HAPO and HAPO Follow-Up Study; newborn and child (age 11–14 years) outcomes4,160 dyads at child follow-up
- Participants
- 7,970 participants
- Comparison
- Gestational diabetes mellitus (GDM) subtypes vs normal glucose tolerance
Methodological detailscohort, adjusted for field center, maternal BMI and other pregnancy covariates
- Cohort
- Adjusted for field center, maternal BMI and other pregnancy covariates
Primary result
As reported in the abstract
Each group vs normal glucose toleranceOdds ratio (95% CI)
Insulin-resistant GDMchildhood obesity
1.53(1.127–2.08)
Insulin-resistant GDMchildhood impaired glucose tolerance
2.21(1.50–3.25)
Mixed-defect GDMchildhood impaired glucose tolerance
3.01(1.47–6.19)
Original publication
Subtypes of Gestational Diabetes Mellitus Are Differentially Associated With Newborn and Childhood Metabolic Outcomes. Diabetes Care. Published 9 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →