Stress hyperglycemia predicts early neurological deterioration and poor outcomes in patients with single subcortical infarct
Main finding · ENDResult — go to the resultOdds ratio 4.04 95% CI 2.43–6.69Authors' conclusion
SHR is a reliable predictor of END and poor outcomes in patients with SSI.
Study context
- Population
- Patients with single subcortical infarct (SSI) admitted 2015–2021; average age 59.49 years
- Participants
- 1,049 patients
- Exposure
- Highest vs lowest stress hyperglycemia ratio quartile
- Outcome
- Early neurological deterioration (END): increase of ≥2 total National Institutes of Health Stroke Scale (NIHSS) points or ≥1 point in NIHSS motor items
- Follow-up
- Within 7 days of hospital admission
Methodological detailsmultivariate logistic regression
- Multivariate logistic regression
Main finding
END · within 7 days of admission
Odds ratio
4.04
95% CI 2.43–6.69
P < 0.001
Highest SHR quartilevs Lowest SHR quartile
OR 4.04 (95% CI 2.43–6.69); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Poor outcome (mRS >2) · 3 monthsMultivariate logistic regression | 2.34 (1.44–3.82) | P = 0.001 | |
| 0.20.5125Odds ratio (log scale) |
Diagnostic accuracy (ROC AUC) of stress hyperglycemia ratio (SHR)
- SHR diagnostic accuracy equal or greater than FPG
Original publication
Stress hyperglycemia predicts early neurological deterioration and poor outcomes in patients with single subcortical infarct. Diabetes Res Clin Pract. Published 29 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →