Type 2 & other diabetes

Effects of weight loss on cognitive function in patients with diabetes: A systematic review and meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis

Pooled result · Cognitive changes with weight lossResult — go to the resultSMD 0.50 95% CI −0.09 to 1.08

Authors' conclusion

Weight loss may be neutral to cognitive function in diabetes, but further studies are required to draw more definitive conclusions.

Study context

Population
Patients with diabetes; Embase, Cochrane Library, PubMed and Web of Science searched from inception to December 18, 2022
Participants
619 patients5 studies
Comparison
Weight loss vs no weight loss
Outcome
Cognitive changes
Methodological detailsrandom-effects model, no study type restrictions
  • Random-effects model
  • No study type restrictions

Pooled result

Cognitive changes with weight loss

SMD

0.50

95% CI −0.09 to 1.08

Weight loss (significant BMI decrease)vs no weight loss
SMD 0.50 (95% CI −0.09 to 1.08)

As reported in the abstract

Further pooled results

Subgroups by duration of intervention/observation and size of body mass index (BMI) reduction

Not significantly affected by duration of intervention or observation, or size of BMI reduction
Effects of interventions and baseline BMI: no definitive conclusions, only one study included

Original publication

Effects of weight loss on cognitive function in patients with diabetes: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 25 April 2023. doi:10.1016/j.diabres.2023.110687

Composed by AI from the published abstract and checked against it. How Briefs are made →

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