Stable Incidence and Increasing Prevalence of Primary Hyperparathyroidism in a Population-based Study in Scotland
Authors' conclusion
This study is the first showing a relatively steady annual incidence of PHPT at 4 to 6 per 10 000 person-years. This population-based study reports a PHPT prevalence of 0.84%.
Study context
- Population
- People with incident primary hyperparathyroidism (PHPT) in Tayside (Scotland), 2007–2018; 72.3% female, mean age 65 years
- Participants
- 2,118 incident PHPT cases
- Outcome
- Incidence and prevalence of PHPT
- Follow-up
- 2007 to 2018
Methodological detailsrecord-linkage, community-based
- Record-linkage
- Community-based
Main finding
As reported in the abstract
2007–2018
- Overall prevalence of PHPT over 12 years
- 0.84% (95% CI 0.68%-1.02%)
- Prevalence in 2007
- 0.71%
- Prevalence in 2018
- 1.02%
- Incidence from 2008, relatively stable (per 10 000 person-years)
- 4 to 6
- Incidence in 2007 (per 10 000 person-years)
- 11.5
Observational data: associations, not effects.
Further findings
Incidence of PHPT by age
- Aged 20 to 29 years, per 10 000 person-years
- 0.59 (95% CI, 0.40%-0.77%)
- Aged 70 to 79 years, per 10 000 person-years
- 12.4 (95% CI, 11.2%-13.3%)
Incidence of PHPT by sex
- Incidence higher in women than in men (times)
- 2.5
Original publication
Stable Incidence and Increasing Prevalence of Primary Hyperparathyroidism in a Population-based Study in Scotland. J Clin Endocrinol Metab. Published 6 April 2023. doi:10.
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