Gestational diabetes & diabetes in pregnancy
Sleep Patterns During Pregnancy, Genetic Susceptibility and Progression From Gestational Diabetes Mellitus to Postpartum Glucose Intolerance: A Prospective Cohort Study
Authors' conclusion
A healthy prenatal sleep pattern was related to a lower PGI risk among women with GDM, regardless of genetic susceptibility.
Study context
- Population
- Women with Gestational Diabetes Mellitus (GDM) in Guangzhou, China (2022–2024)
- Participants
- 897 women
- Exposure
- Intermediate or healthy vs unhealthy prenatal sleep pattern
- Outcome
- PGI, ascertained via a 75-g OGTT
- Follow-up
- 4-12 weeks postpartum
Main finding
As reported in the abstract
PGI
Each group vs unhealthy sleep patternRelative risk (95% CI)
Intermediate sleep pattern
0.77(0.61–0.98)
Healthy sleep pattern
0.70(0.54–0.92)
- Developed postpartum glucose intolerance (PGI) overall
- 255 women (28.4%)
Observational data: associations, not effects.
Further findings
| Outcome | β (95% CI) |
|---|---|
| Postpartum fasting glucoseHealthy sleep pattern vs Unhealthy sleep pattern | −0.158 (−0.239 to −0.078) |
Postpartum 2-h glucose
- Healthy sleep pattern not related to 2-h glucose
Joint effect of sleep pattern and T2DM polygenic risk score (154 variants) on PGI
- Highest PGI risk among women with unhealthy sleep pattern and high genetic risk
Original publication
Sleep Patterns During Pregnancy, Genetic Susceptibility and Progression From Gestational Diabetes Mellitus to Postpartum Glucose Intolerance: A Prospective Cohort Study. Diabetes Obes Metab. Published 30 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →