Skeletal Muscle Gene Expression Signatures of Obese High and Low Responders to Endurance Exercise Training
Authors' conclusion
Together, our data offer an insight into molecular mechanisms underlying differences in response to exercise and provide potential novel markers for the success of intervention.
Study context
- Population
- People with obesity undergoing 8 weeks of supervised endurance training; skeletal muscle gene expression and DNA methylation before and after intervention
- Comparison
- Low responders vs high responders to endurance training
- Outcome
- Skeletal muscle gene expression and DNA methylation signatures
Methodological detailssupervised endurance training, 8 weeks
- Supervised endurance training
- 8 weeks
Main finding
As reported in the abstract
Differences in gene expression linked to differences in DNA methylation
Between 45% and 70%
Original publication
Skeletal Muscle Gene Expression Signatures of Obese High and Low Responders to Endurance Exercise Training. J Clin Endocrinol Metab. Published 21 November 2023. doi:10.
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