Sitting Time Reduction and Blood Pressure in Older Adults: A Randomized Clinical Trial
Authors' conclusion
In this study of a 6-month sitting reduction intervention, older adults in the intervention reduced sedentary time by more than 30 min/d and reduced systolic blood pressure. Sitting reduction could be a promising approach to improve health in older adults.
Study context
- Population
- Adults aged 60 to 89 years with high sitting time and BMI 30 to 50, health care system in Washington State, 2019–2022; mean age 68.8 years, 65.7% female, 51.9% with hypertensionrandomized 1:1
- Participants
- 283 adults
- Comparison
- Sitting reduction intervention vs healthy living attention control for 6 months
- Interventionn = 140
- Controln = 143reference
- Primary endpoint
- Sitting time by accelerometers worn for 7 days; coprimary: systolic and diastolic BP
- Follow-up
- 3 and 6 months (BP at 6 months)
Methodological detailsparallel-group, attention-controlled
- Parallel-group
- Attention-controlled
Primary result
As reported in the abstract
Difference in mean change in sitting time, min/d (95% CI)P value
Interventionvs Control3 months
−31.44(−48.69 to −14.19)
P < 0.001Interventionvs Control6 months
−31.85(−52.91 to −10.79)
P = 0.003- Between Intervention and Control · 6 months; lower with Intervention
- difference in systolic BP change 3.48 mm Hg (95% CI −6.68 to −0.28); P = 0.03
Safety
Events
| Outcome | Intervention | Control |
|---|---|---|
| Serious adverse events | 6 | 6 |
Serious adverse events
- None study related
Original publication
Sitting Time Reduction and Blood Pressure in Older Adults: A Randomized Clinical Trial. JAMA Netw Open. Published 4 March 2024. doi:10.
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