Use of Diabetes Technologies and Retinopathy in Adults With Type 1 Diabetes
Authors' conclusion
In this cohort study of adults with T1D, CGM use was associated with lower odds of developing DR and PDR, even after adjusting for HbA1c. These findings suggest that CGM may be useful for diabetes management to mitigate risk for DR and PDR.
Study context
- Population
- Adults with T1D at a tertiary diabetes center and ophthalmology center, 2013–2021; median age 40 (IQR 28–54) years, 54.4% female, median diabetes duration 20 (IQR 10–30) years, median hemoglobin A1c (HbA1c) 7.8%
- Participants
- 550 adults
- Exposure
- Continuous glucose monitoring (CGM) use vs no CGM use
- Outcome
- Development of DR or PDR
Methodological detailstertiary diabetes center and ophthalmology center
- Tertiary diabetes center and ophthalmology center
Main finding
As reported in the abstract
CGM vs No CGMOdds ratio (95% CI)P value
DR; multivariable adjusted incl. mean HbA1c
0.52(0.32–0.84)
P = 0.008PDR; multivariable adjusted incl. mean HbA1c
0.42(0.23–0.75)
P = 0.004- Participants with diabetic retinopathy (DR) at any point
- 44% (244 of 550)
Observational data: associations, not effects.
Secondary outcomes
Progression of DR (longitudinal cohort without baseline proliferative diabetic retinopathy (PDR)) · during the study
- Progression of DR
- 79 of 363 (21.8%)
Original publication
Use of Diabetes Technologies and Retinopathy in Adults With Type 1 Diabetes. JAMA Netw Open. Published 4 March 2024. doi:10. 1001/ jamanetworkopen. 2024. 0728
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