Diabetes technology

Use of Diabetes Technologies and Retinopathy in Adults With Type 1 Diabetes

JAMA Netw OpenPublished Retrospective cohort study

Authors' conclusion

In this cohort study of adults with T1D, CGM use was associated with lower odds of developing DR and PDR, even after adjusting for HbA1c. These findings suggest that CGM may be useful for diabetes management to mitigate risk for DR and PDR.

Study context

Population
Adults with T1D at a tertiary diabetes center and ophthalmology center, 2013–2021; median age 40 (IQR 28–54) years, 54.4% female, median diabetes duration 20 (IQR 10–30) years, median hemoglobin A1c (HbA1c) 7.8%
Participants
550 adults
Exposure
Continuous glucose monitoring (CGM) use vs no CGM use
Outcome
Development of DR or PDR
Methodological detailstertiary diabetes center and ophthalmology center
  • Tertiary diabetes center and ophthalmology center

Main finding

As reported in the abstract

CGM vs No CGMOdds ratio (95% CI)P value
DR; multivariable adjusted incl. mean HbA1c
0.52(0.32–0.84)
P = 0.008
PDR; multivariable adjusted incl. mean HbA1c
0.42(0.23–0.75)
P = 0.004
Participants with diabetic retinopathy (DR) at any point
44% (244 of 550)

Observational data: associations, not effects.

Secondary outcomes

Progression of DR (longitudinal cohort without baseline proliferative diabetic retinopathy (PDR)) · during the study

Progression of DR
79 of 363 (21.8%)

Original publication

Use of Diabetes Technologies and Retinopathy in Adults With Type 1 Diabetes. JAMA Netw Open. Published 4 March 2024. doi:10.1001/jamanetworkopen.2024.0728

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