Sitting Time and Its Interaction With Physical Activity in Relation to All-Cause and Heart Disease Mortality in U.S. Adults With Diabetes
Authors' conclusion
In adults with diabetes, meeting guideline-recommended physical activity may offset the elevated all-cause and heart disease mortality risk associated with excessive sitting time.
Study context
- Population
- US adults with diabetes, NHANES 2007–2018, mortality follow-up through 2019; mean age 59.6 years, 48.3% female
- Participants
- 6,335 adults
- Exposure
- Longer vs shorter sitting time, by moderate to vigorous physical activity (MVPA) level
- Outcome
- All-cause and heart disease mortality
- Follow-up
- Median 5.9 years
Methodological detailspopulation-based, Cox models adjusted for sociodemographics, lifestyle factors and medical conditions
- Population-based
- Cox models adjusted for sociodemographics, lifestyle factors and medical conditions
Main finding
As reported in the abstract
- All-cause mortality interaction
- P = 0.003 for interaction
- Heart disease mortality interaction
- P = 0.008 for interaction
- All-cause deaths
- 1,278
- Heart disease deaths
- 354
Observational data: associations, not effects.
Original publication
Sitting Time and Its Interaction With Physical Activity in Relation to All-Cause and Heart Disease Mortality in U.S. Adults With Diabetes. Diabetes Care. Published 19 July 2024. doi:10.
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