Type 2 & other diabetes

Association of Weekend Warrior and Other Physical Activity Patterns With Mortality Among Adults With Diabetes : A Cohort Study

Ann Intern MedPublished Prospective cohort study

Authors' conclusion

Weekend warrior and regularly active physical activity patterns meeting current physical activity recommendations (MVPA ≥150 minutes per week) were associated with 21% and 17% lower risks for all-cause mortality and 33% and 19% lower hazards of cardiovascular mortality among adults with diabetes compared with those with diabetes who are physically inactive.

Study context

Population
US adults with self-reported diabetes, National Health Interview Survey (1997 to 2018) linked to National Death Index through 31 December 2019
Participants
51,650 adults
Exposure
Weekend warrior, regularly active and insufficiently active vs inactive physical activity patterns
Outcome
All-cause mortality
Follow-up
Median 9.5 years
Methodological detailsPhysical activity self-reported and assessed at a single time point
  • Physical activity self-reported and assessed at a single time point

Main finding

As reported in the abstract

Multivariable-adjusted
Each group vs inactiveHazard ratio (95% CI)
Insufficiently active
0.90(0.85–0.95)
Weekend warrior
0.79(0.69–0.91)
Regularly active
0.83(0.78–0.87)
Deaths documented (cardiovascular, 5620; cancer, 2883)
16 345

Observational data: associations, not effects.

Further findings

OutcomeHR (CI)
Cardiovascular mortalityInsufficiently activevs Inactive0.98 (0.89–1.07)
Cardiovascular mortalityWeekend warriorvs Inactive0.67 (0.52–0.86)
Cardiovascular mortalityRegularly activevs Inactive0.81 (0.74–0.88)
Cancer mortalityInsufficiently activevs Inactive0.88 (0.78–1.00)
Cancer mortalityWeekend warriorvs Inactive0.99 (0.76–1.30)
Cancer mortalityRegularly activevs Inactive0.85 (0.75–0.96)

Original publication

Association of Weekend Warrior and Other Physical Activity Patterns With Mortality Among Adults With Diabetes : A Cohort Study. Ann Intern Med. Published 22 July 2025. doi:10.7326/annals-25-00640

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