Service evaluation suggests variation in clinical care provision in adults with congenital adrenal hyperplasia in the UK and Ireland
Authors' conclusion
Differences in current management of CAH continue to exist. It appears crucial to objectify if different approaches result in different long-term outcomes. New studies such as CaHASE2, incorporating standardised minimum datasets including replacement therapies and monitoring strategies as well as longitudinal data collection, are now needed to define best-practice and standardise care.
Study context
- Population
- Clinicians managing adults with congenital adrenal hyperplasia (CAH) in the UK and Ireland; members of the Society for Endocrinology and Irish Endocrine Society
- Exposure
- General endocrinology vs subspecialist settings
- Outcome
- CAH management practices
Methodological detailsanonymised online survey, service evaluation
- Anonymised online survey
- Service evaluation
Main finding
As reported in the abstract
- Marked variability in CAH management, with differences between general endocrinology and subspecialist settings, particularly in glucocorticoid use, biochemical monitoring and comorbidity screening
- Between General endocrinology and Subspecialist: P = 0.002
- Between General endocrinology and Subspecialist: P = 0.0004
- Between General endocrinology and Subspecialist: P < 0.0001
Observational data: associations, not effects.
Further findings
Use of the I-CAH registry
- Adoption of the I-CAH registry was universally low
Original publication
Service evaluation suggests variation in clinical care provision in adults with congenital adrenal hyperplasia in the UK and Ireland. Clin Endocrinol (Oxf). Published 17 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →