Serum scEMC10 Levels are Negatively Associated With Resting Metabolic Rate and age in Humans
Authors' conclusion
Serum scEMC10 levels are negatively associated with age and RMR in humans.
Study context
- Population
- Chinese physical examination cohort and Leipzig Obesity Biobank cohortChinese and Leipzig cohorts · Chinese physical examination cohort 833 · Leipzig Obesity Biobank cohort 191
- Outcome
- Associations of serum scEMC10 with BMI, RMR and age
Methodological detailsscEMC10 measured by chemiluminescent immunoassay; Resting metabolism rate (RMR) by indirect calorimetry (open-circuit ventilated-hood)
- scEMC10 measured by chemiluminescent immunoassay; RMR by indirect calorimetry (open-circuit ventilated-hood)
Main finding
As reported in the abstract
Serum scEMC10 associations
- J-shaped nonlinear correlation between body mass index (BMI) and serum scEMC10; underweight, overweight and obese had higher levels than normal weight (Chinese cohort)
- Age <30 y had significantly higher scEMC10 than >50 y; age 30–40 y higher than 50–60 y (Chinese cohort)
- Significantly negative correlation between scEMC10 and resting energy expenditure after adjusting for BMI (Leipzig cohort)
- Highest scEMC10 quartile had significantly lower RMR than first quartile
- RMR independently inversely associated with serum scEMC10
Observational data: associations, not effects.
Original publication
Serum scEMC10 Levels are Negatively Associated With Resting Metabolic Rate and age in Humans. J Clin Endocrinol Metab. Published 18 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →