Serum 25(OH)D and diabetes risk in adults with prediabetes: evidence, potential mechanisms, and implications
Authors' conclusion
These findings indicate a potential role for a precision nutrition approach with high-dose vitamin D supplementation to lower risk of type 2 diabetes in adults with prediabetes.
Study context
- Population
- Adults with prediabetes
- Outcome
- Diabetes risk with vitamin D supplementation
Main finding
As reported in the abstract
- Vitamin D supplementation at doses sufficient to achieve 25-hydroxyvitamin D levels ≥ 40 ng/ml appears to confer additional benefit in reducing diabetes risk in subsets of the population with prediabetes
Original publication
Serum 25(OH)D and diabetes risk in adults with prediabetes: evidence, potential mechanisms, and implications. J Clin Endocrinol Metab. Published 12 November 2026. doi:10. 1210/ clinem/ dgag460
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