Obesity

Semaglutide for cardiovascular event reduction in people with overweight or obesity: SELECT study baseline characteristics

Obesity (Silver Spring)Published Descriptive report of baseline characteristics of the SELECT randomised trial

Authors' conclusion

The enrolled population in SELECT includes participants across a broad range of relevant risk categories. This will allow the study to garner information about the CV benefits of semaglutide across these relevant clinical subgroups.

Study context

Population
Individuals with overweight or obesity without diabetes, with prior MI, stroke and/or peripheral artery disease72.5% male
Participants
17,605 individuals
Comparison
Semaglutide vs placebo; baseline characteristics reported

Primary result

As reported in the abstract

Baseline characteristics
Age, mean (SD)
61.6 (8.9) years
BMI, mean (SD)
33.34 (5.04) kg/m²
Prior MI
76.3%
Prior stroke
23.3%
Peripheral artery disease
8.6%
HF diagnosis
24.3%
HbA1c in prediabetes range (5.7%-6.4%)
66%

Further findings

Cardiovascular (CV) risk factors across HbA1c subgroups · baseline

Across groups of increasing HbA1c, prevalence of all CV risk factors increased

Original publication

Semaglutide for cardiovascular event reduction in people with overweight or obesity: SELECT study baseline characteristics. Obesity (Silver Spring). Published 10 December 2022. doi:10.1002/oby.23621

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.