Self-management and hospitalization in 615 Swedish patients with Addison's disease during the coronavirus disease 2019 pandemic: a retrospective study
Authors' conclusion
In the largest study to date examining AAD during the COVID-19 pandemic, we observed that although one-fifth of the cohort contracted COVID-19, few patients required hospital care. A majority of the patients applied general recommended sick rules despite reporting limited communication with healthcare during the pandemic.
Study context
- Population
- Adults with autoimmune Addison's disease in the Swedish Addison Registry; questionnaires April–October 2021, focus on pre-vaccine phase of COVID-19 pandemic813 sent questionnaires
- Participants
- 615 adults
- Outcome
- Incidence of COVID-19 in patients with Autoimmune Addison's disease (AAD)
Methodological detailsquestionnaire-based, national registry (Swedish Addison Registry)
- Questionnaire-based
- National registry (Swedish Addison Registry)
Main finding
As reported in the abstract
COVID-19 reported
COVID-19 reported
17%
Observational data: associations, not effects.
Further findings
Hospital care among COVID-19 cases
- Required hospital care
- 8.5%
Glucocorticoid self-adjustment
- Outpatients who increased glucocorticoid dosage during sickness
- 85%
- Glucocorticoid treatment in hospitalized patients varied
Risk factors for hospital care
- Older age associated with increased risk of hospital care
- P = 0.002
- Hypertension associated with increased risk of hospital care
- P = 0.014
Risk factors for COVID-19
- Younger age correlated with higher risk of COVID-19
- P < 0.001
- Less worry about infection correlated with higher risk of COVID-19
- P = 0.030
Original publication
Self-management and hospitalization in 615 Swedish patients with Addison's disease during the coronavirus disease 2019 pandemic: a retrospective study. Eur J Endocrinol. Published 31 January 2023. doi:10.
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