Income and work loss in patients with Addison's disease: a nationwide population-based study
Main finding · Work loss, taxable earnings and disposable incomeResult — go to the resultAdjusted mean difference 14.4 days 95% CI 8.6–20Authors' conclusion
Patients with AAD had more work loss, yet overall similar taxable earnings and disposable incomes versus comparators. Patients with AAD with shorter education or type 1 diabetes were most socioeconomically vulnerable.
Study context
- Population
- Working-age (18–64 years) individuals, Swedish Addison Register linked to national health registers; mean age 46.1 years, 48.4% menmatched 1:5
- Participants
- 1,140 vs 5,700
- Exposure
- Autoimmune Addison's disease (AAD) vs matched general population comparators
- AADn = 1,140
- Comparatorsn = 5,700reference
- Outcome
- Differences in income (taxable earnings, disposable income) and work loss
- Follow-up
- 2019
Methodological detailsnationwide, register-based, matched 1:5 by sex, age and county of residence
- Nationwide
- Register-based
- Matched 1:5 by sex, age and county of residence
Main finding
As reported in the abstract
Work loss, taxable earnings and disposable income
Adjusted mean difference
14.4 days
95% CI 8.6–20
AADvs Comparators
adjusted mean difference 14.4 days (95% CI 8.6–20)
- Adjusted median difference in taxable earnings, overall (non-significant)
- −617 € (95% CI; −2317 to 1083)
- Adjusted median difference in disposable income, overall (non-significant)
- −405 € (95% CI; −1417 to 607)
Observational data: associations, not effects.
Further findings
T1D prevalence
Taxable earnings and disposable income, subgroup with short education · 2019
- Significantly lower taxable earnings in patients with short education
- −5303 € (95% CI; −9603 to −992)
- Significantly lower disposable income in patients with short education
- −3754 € (95% CI; −6486 to −1022)
Taxable earnings and disposable income, subgroup with concomitant T1D · 2019
- Significantly lower taxable earnings in patients with concomitant T1D
- −5808 € (95% CI; −9937 to −1690)
- Significantly lower disposable income in patients with concomitant T1D
- −3349 € (95% CI; −6203 to −506)
Original publication
Income and work loss in patients with Addison's disease: a nationwide population-based study. Eur J Endocrinol. Published 21 February 2025. doi:10.
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