SCORE2-diabetes for predicting coronary artery disease: a cardiac CT study in a diabetic moderate-risk region population
Authors' conclusion
Higher SCORE2-D scores correlate with greater CAD burden, more severe stenosis, and a predominance of high-risk plaque features in patients with T2DM. These findings suggest that SCORE2-D may be a valuable tool in refining cardiovascular risk stratification and guiding clinical decision-making in diabetic populations.
Study context
- Population
- Patients aged 40–69 with T2D, no history of atherosclerotic CVD and no severe target organ damage, undergoing CCTA at a tertiary care center; mean age 60.9 years
- Participants
- 104 patients
- Exposure
- SCORE2-Diabetes (SCORE2-D) risk categories
- Outcome
- Association of SCORE2-D risk category with presence, morphology and severity of coronary plaques on CCTA
Methodological detailssingle tertiary care centre, CCTA-based
- Single tertiary care centre
- CCTA-based
Main finding
As reported in the abstract
Coronary artery disease (CAD) on CCTA by SCORE2-D
Mean SCORE2-D
12.2 ± 4.9
Observational data: associations, not effects.
Further findings
Referral for invasive coronary angiography
- Higher-risk patients more often referred for invasive coronary angiography
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
SCORE2-diabetes for predicting coronary artery disease: a cardiac CT study in a diabetic moderate-risk region population. Cardiovasc Diabetol. Published 29 December 2025. doi:10.
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