Sarcopenia definitions and their association with injurious falls in older Swedish women from the Sahlgrenska University Hospital Prospective Evaluation of Risk of Bone fractures (SUPERB) study
Authors' conclusion
Sarcopenia definitions confined to muscle function and strength such as SDOC, rather than including DXA-determined ALMI (EWGSOP2 and AWGS), are associated with incident injurious falls with and without fractures in older women.
Study context
- Population
- Women aged 75–80 years with complete data on sarcopenia definitions, Swedish SUPERB cohort
- Participants
- 2,883 women
- Exposure
- Sarcopenia by Sarcopenia Definitions and Outcomes Consortium (SDOC), EWGSOP2 and AWGS definitions vs no sarcopenia
- Outcome
- Incident injurious falls (with and without fracture), identified via national registers
- Follow-up
- Median 7.06 (IQR 6.2-7.9) years
Methodological detailspopulation-based, Cox regression, unadjusted and adjusted for age, BMI, previous falls and Charlson comorbidity index
- Population-based
- Cox regression, unadjusted and adjusted for age, BMI, previous falls and Charlson comorbidity index
Main finding
As reported in the abstract
Injurious falls · median 7.06 years
SDOCHazard ratio (95% CI)
Injurious falls including fracture
2.11(1.63–2.73)
Injurious falls without fracture
2.16(1.55–3.02)
- Injurious falls without fracture
- 491
- Injurious falls incl. fracture
- 962
Observational data: associations, not effects.
Original publication
Sarcopenia definitions and their association with injurious falls in older Swedish women from the Sahlgrenska University Hospital Prospective Evaluation of Risk of Bone fractures (SUPERB) study. Osteoporos Int. Published 6 August 2024. doi:10.
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