Salivary glycated albumin could be as reliable a marker of glycemic control as blood glycated albumin in people with diabetes
Authors' conclusion
This exploratory research revealed that the salivary GA levels by this method were accurate and might be able to replace blood GA measurement. The home salivary GA measurement is expected to be developed that may reduce the burden and complications in people with diabetes mellitus and improve the quality of life.
Study context
- Population
- People with DM admitted to The University of Tokyo Hospital
- Participants
- 56 people
- Comparison
- Salivary glycated albumin (GA) vs blood GA measured by high-performance liquid chromatography (HPLC)
- Outcome
- Correlation between GA levels measured in blood and saliva
- Follow-up
- Fasting and 2-hour postprandial at admission and fasting at discharge
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Correlation of blood and salivary GA
Fasting at admission (n = 45): R2
0.985
P < 0.001
2-hour postprandial at admission (n = 48): R2
0.973
P < 0.001
Fasting at discharge (n = 51): R2
0.979
P < 0.001
Further findings
Multiple regression
- Associations maintained after adjustment for age, BMI and nephropathy stage
Original publication
Salivary glycated albumin could be as reliable a marker of glycemic control as blood glycated albumin in people with diabetes. Diabetes Res Clin Pract. Published 22 October 2024. doi:10.
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