Obesity

Risk associated with planned mode of delivery in women with obesity: a large population-based retrospective cohort study

Int J Obes (Lond)Published Population-based retrospective cohort study

Authors' conclusion

Among women with obesity, NLCS may be considered as an option for planned mode of delivery due to the decreased AOI risk. However, further research on the association between NLCS and severe outcomes is needed. Shared decision making between patient and practitioner regarding plan for delivery remains paramount in the provision of quality obstetrical care.

Study context

Population
Nulliparous women with obesity with live, singleton, uncomplicated term gestations, April 2012–March 2019
Participants
27,472 women
Exposure
Planned non-labor cesarean section (NLCS) or planned induction of labor vs spontaneous labor
Outcome
Adverse Outcome Index (AOI), binary composite of 10 maternal-neonatal outcomes
Methodological detailsmultivariable regression, stratified by week of gestational age and obesity class
  • Multivariable regression
  • Stratified by week of gestational age and obesity class

Main finding

As reported in the abstract

Overall, maternal-specific and neonatal-specific AOI · term gestation
Each group vs spontaneous laborEstimate (95% CI)
Planned NLCSrisk reduced by 41%
aRR, overall AOI 0.59(0.50–0.70)
Planned NLCSrisk reduced by 54%
aRR, maternal-specific AOI 0.46(0.35–0.60)
Planned NLCSrisk reduced by 30%
aRR, neonatal-specific AOI 0.70(0.57–0.87)
Planned induction of labor
aRR, overall AOI 1.03(0.96–1.10)

Observational data: associations, not effects.

Original publication

Risk associated with planned mode of delivery in women with obesity: a large population-based retrospective cohort study. Int J Obes (Lond). Published 17 March 2025. doi:10.1038/s41366-024-01709-x

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