Pre-labor and post-labor cesarean delivery and early childhood adiposity in the Canadian Healthy Infant Longitudinal Development (CHILD) Cohort Study
Main finding · OverweightResult — go to the resultAdjusted odds ratio 1.68 95% CI 1.05–2.67Authors' conclusion
Our findings add to the body of evidence that CS, in particular CS without labor events, may be a risk factor for overweight in early life, and that this association may be sex-specific. These findings could help to identify children at higher risk for developing obesity.
Study context
- Population
- Mother-infant pairs from the CHILD Cohort Study in Canada; children aged 1–5 years
- Participants
- 3,073 mother-infant pairs
- Exposure
- Cesarean section (CS) with or without labor events vs vaginal delivery
- Outcome
- Overweight by age and sex adjusted weight-for-length (WFL) and BMI z scores
- Follow-up
- 1, 3 and 5 years
Main finding
Overweight · 1 year
Adjusted odds ratio
1.68
95% CI 1.05–2.67
CS without laborvs Vaginal delivery
aOR 1.68 (95% CI 1.05–2.67)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aOR (95% CI) | |
|---|---|---|
| Overweight, boys (sex-stratified) · 1 yearCS without laborvs Vaginal deliveryEffect only seen in boys | 2.21 (1.26–3.88) | |
| 0.20.5125Adjusted odds ratio (log scale) |
Delivery mode distribution
- Born by CS
- 24.6%
- CS with labor events
- 13.0%
- CS without labor events
- 11.6%
Original publication
Pre-labor and post-labor cesarean delivery and early childhood adiposity in the Canadian Healthy Infant Longitudinal Development (CHILD) Cohort Study. Int J Obes (Lond). Published 1 February 2024. doi:10. 1038/ s41366-024-01480-z
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