Obesity

Pre-labor and post-labor cesarean delivery and early childhood adiposity in the Canadian Healthy Infant Longitudinal Development (CHILD) Cohort Study

Int J Obes (Lond)Published Prospective cohort study

Main finding · OverweightResult — go to the resultAdjusted odds ratio 1.68 95% CI 1.05–2.67

Authors' conclusion

Our findings add to the body of evidence that CS, in particular CS without labor events, may be a risk factor for overweight in early life, and that this association may be sex-specific. These findings could help to identify children at higher risk for developing obesity.

Study context

Population
Mother-infant pairs from the CHILD Cohort Study in Canada; children aged 1–5 years
Participants
3,073 mother-infant pairs
Exposure
Cesarean section (CS) with or without labor events vs vaginal delivery
Outcome
Overweight by age and sex adjusted weight-for-length (WFL) and BMI z scores
Follow-up
1, 3 and 5 years

Main finding

Overweight · 1 year

Adjusted odds ratio

1.68

95% CI 1.05–2.67

CS without laborvs Vaginal delivery
aOR 1.68 (95% CI 1.05–2.67)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeaOR (95% CI)
Overweight, boys (sex-stratified) · 1 yearCS without laborvs Vaginal deliveryEffect only seen in boys2.21 (1.26–3.88)

Delivery mode distribution

Born by CS
24.6%
CS with labor events
13.0%
CS without labor events
11.6%

Original publication

Pre-labor and post-labor cesarean delivery and early childhood adiposity in the Canadian Healthy Infant Longitudinal Development (CHILD) Cohort Study. Int J Obes (Lond). Published 1 February 2024. doi:10.1038/s41366-024-01480-z

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