Osteoporosis, bone & mineral

Return on investment of fracture liaison services: a systematic review and analysis

Osteoporos IntPublished Systematic review and analysis

Authors' conclusion

This review revealed a 10.49-fold monetary return of FLS.

Study context

Population
Patients with an existing fragility fracture; studies on cost-effectiveness of fracture liaison services (FLS) published January 2000–December 202223 FLS
Outcome
Return on investment (ROI) of FLS: (monetary benefits − FLS costs) / FLS costs
Methodological detailssubgroup analysis across FLS types and design details, Searched MEDLINE, EMBASE, PubMed and Cochrane Central, Two independent reviewers for study selection and data extraction
  • Subgroup analysis across FLS types and design details
  • Searched MEDLINE, EMBASE, PubMed and Cochrane Central
  • Two independent reviewers for study selection and data extraction

Pooled result

As reported in the abstract

ROI of FLS

Mean return on investment (ROI)

10.49

Median ROI

7.57

FLS with positive ROI

86.96%

Further pooled results

ROI, FLS making treatment recommendations (highest ROI)

Mean ROI
18.39
Median ROI
13.60

ROI, FLS incorporating primary care providers

Mean ROI
16.04
Median ROI
13.20

ROI, FLS with primary care providers as program leaders

Mean ROI
12.07
Median ROI
12.07

ROI by FLS type

Intensive type A and B FLS had higher ROI than non-intensive type C and D FLS
FLS for specific fracture sites had great monetary return

Original publication

Return on investment of fracture liaison services: a systematic review and analysis. Osteoporos Int. Published 1 February 2024. doi:10.1007/s00198-024-07027-2

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