Diabetes technology

The results of ProHCL: Patient-reported outcomes in people living with type 1 diabetes on hybrid closed-loop insulin pump therapy − experiences from the NHS England pilot

Diabetes Res Clin PractPublished Cross-sectional study

An erratum to this article was published (Diabetes Res Clin Pract, Jul 2026 ↗)

Authors' conclusion

HCL therapy is associated with improved PROs in PwT1D. However, system usability significantly influences outcomes, and alarm and data burden remain concerns.

Study context

Population
People with T1D enrolled on the NHS England HCL pilot, and their partners
Outcome
Patient-reported outcomes (PROs) in PwT1D after ≥3 months of HCL
Methodological detailsquantitative component of mixed-methods study, online questionnaires, Self-reported clinical data collected
  • Quantitative component of mixed-methods study
  • Online questionnaires
  • Self-reported clinical data collected

Main finding

As reported in the abstract

INSPIRE score (0-100), median IQR

88/100

IQR 73–95

DTSQc score (−18 to +18)

17 of 18

14–18

INSPIRE: strongly agree HCL improved HbA1c, TIR and overall quality of life

>70 %

DTSQc: blood glucose unacceptably low/high much less of the time since starting HCL

>70 %

Observational data: associations, not effects.

Further findings

Usability (SUS score)

Those finding HCL harder to use had lower INSPIRE, DTSQs and DTSQc scores and higher HbA1c than those finding it easier

Safety

Burden of HCL

%

Increased alarm burden
54.4
Information overload
21.6

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The results of ProHCL: Patient-reported outcomes in people living with type 1 diabetes on hybrid closed-loop insulin pump therapy − experiences from the NHS England pilot. Diabetes Res Clin Pract. Published 6 January 2026. doi:10.1016/j.diabres.2026.113084

Composed by AI from the published abstract and checked against it. How Briefs are made →

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